Search on: PHOSPHOFRUCTOKINASE-1, TYPE C 
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Descriptor English:   Phosphofructokinase-1, Type C 
Descriptor Spanish:   Fosfofructoquinasa-1 Tipo C 
Descriptor Portuguese:   Fosfofrutoquinase-1 Tipo C 
Synonyms English:   6-Phosphofructokinase, Platelet Type  
Tree Number:   D08.811.913.696.620.225.850.500.750
Definition English:   An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits. 
History Note English:   2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   36115 
Unique Identifier:   D025502 

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